Is weight-loss surgery properly restoring insulin response?

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Obesity is often accompanied by reduced response to insulin, which can, in turn, develop into type-2 diabetes. Gastric bypass surgery in obese individuals can lead to weight loss and to subsequent restoration of insulin response. Looking at the fat tissue as one major insulin responding tissue, we identified the genes responding to an acute insulin challenge. We compared the insulin response of obese individuals and never obese individuals to the response after weight loss.

24 september 2021
Gymnasiet och åk 9
Carsten Daub, Karolinska Institutet/SciLifeLab